Sh Mirdar; E Asadi; A Arzani; Gh Hamidiyan
Abstract
Aim: Estrogens binding to estrogen receptors in the cytoplasm, causing an increase in the synthesis of DNA, RNA and others proteins in the target tissue. Endurance exercises may affect the expression of estrogen receptors in overectomized rats. Therefore, the aim of present study was to investigate the ...
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Aim: Estrogens binding to estrogen receptors in the cytoplasm, causing an increase in the synthesis of DNA, RNA and others proteins in the target tissue. Endurance exercises may affect the expression of estrogen receptors in overectomized rats. Therefore, the aim of present study was to investigate the effect of six weeks swimming training on expression of estrogen receptors in the uterus and fallopian tubes in overectomized rats.
Method: thirty female Wistar rats with an average weight of 90-110g, were randomly assigned into three groups, consist of control, sham and swimming training. swimming time at first was 30 minutes for each session that daily increased 5 minutes until reached 60 minutes per day in second week and remained 60 minutes to end of training period (6 week). expression of estrogen receptors in fallopian tubes and uterus tissues were measured by immunohistochemistry assay. data analyzed by ANOVA and Tukey test at α≥0.005
Results: The mean levels of estrogen receptors expression in uterus were not significantly different between training with control group. But differences were significant between training and control groups with sham group (P<0.01). expression of estrogen receptors increased %78.43 in sham group and decreased %2.3 in training group in comparison to control group.
Conclusion: the results of present study indicated that six weeks' swimming training haven’t any effect on expression of estrogen receptors in overectomized rat uterus tissue.
َAkram Arzani; Sadmehr Mirdar; Mehdi Hedayati
Volume 4, Issue 2 , December 2015, , Pages 151-158
Abstract
Objective: The aquaporin5 (AQP5) is an integral membrane protein that plays an important role in maintaining water homeostasis in the lung. The purpose of this study was to evaluate the effect of interval training on AQP5 levels in the lung of Male Wistar rats during puberty. Methodology: 30 three-week ...
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Objective: The aquaporin5 (AQP5) is an integral membrane protein that plays an important role in maintaining water homeostasis in the lung. The purpose of this study was to evaluate the effect of interval training on AQP5 levels in the lung of Male Wistar rats during puberty. Methodology: 30 three-week male Wistar rats with average weight of 68±9 g were randomly divided into three groups included; the base, control and training groups. The training group ran on treadmill for 6 weeks (6 per week, 30 minutes each session at a speed of 15 to70 meters per minute). AQP5 levels were measured by ELISA methods. Analyzed is done with two-way ANOVA and LSD test at PResults: Results showed significant differences between AQP5 levels of control, base and training groups (P<0.05). While, there were no significant differencesbetween AQP5 levels of control and base groups . Furthermore, six-weeks interval training increased AQP5 levels of lung tissue in exercise group compared to the control group by 229.03 and 284.9 percent. Conclusion: It seems that an Increased interval training can improve the of epithelial cell performance and protect the AQP5 level changes during the puberty, and improve lung liquid homeostasis.
